Research area
Mitochondria & ageing
Peptides acting on mitochondria, telomeres and metabolic signalling. Contains both the only approved drug in this atlas and some of its least-tested compounds.
Elamipretide (SS-31)
SS-31, MTP-131, bendavia, ForzinityThe only approved drug in this atlas — and a case study in how a real mitochondrial peptide fails most of the trials it enters.
Mitochondria & ageing
FDA-approved for Barth syndrome only
MOTS-c
mitochondrial open reading frame of the 12S rRNA type-c, mitochondrial-derived peptideA peptide written in your mitochondrial genome, not your nuclear one. Fascinating biology, exercise-mimetic claims, no human trial.
Mitochondria & ageing
Not FDA-approved
Epitalon
Epithalon, Epithalone, AEDG peptide, epithalamin-derived tetrapeptideFour amino acids sold as a telomere extender. The telomerase findings are real, in cell culture — and that is also the main reason for concern.
Mitochondria & ageing
Not FDA-approved